It is currently possible to run Twitch ads via SAMMI. However, according to the Twitch documentation, only running ads via the Twitch ad manager qualifies for 55% ad revenue. Running ads via SAMMI would result in 30% ad revenue.

HOWEVER, it is currently very hard for streamer to know WHEN ads are rolled out via the ad manager. I tested it today with 3 minute ads every hour, but there was no notification before the ads were rolled out. Therefore, I request adding a trigger for when ads are rolled out.

With this trigger, streamers could display a notification on stream, or even create an automatic chat message à la "Currently, you may see advertisement. During this time, we won't progress in the game. Grab a snak and we will soon continue with the story!". This can be very handy, as viewers seeing the ad can't hear the streamer, but they can still read the chat.

For reference: https://help.twitch.tv/s/article/ads-manager?language=en_US